Born in New York on May 4, 1878, Dedrick Stuber studied at the Art Students League in New York City and with Bridgman, Julian Onderdonk and Clinton Peters. He also received critiques from the American Barbizon painter Henry Ward Ranger. Stuber's artistic influences included French Barbizon artists Camille Corot and Charles Francois Daubigny.

In New York Stuber painted in the countryside of Westchester County and on Long Island. His paintings were exhibited at the National Academy of Design in 1911 and 1912. He came to California in 1920, settling in Los Angeles where he became an active member of the art community.

Stuber painted the California landscape from San Diego to Monterey. A favorite painting spot was at Lake Elsinore. Although best known for his pastoral subjects, he also painted Los Angeles cityscapes, harbor scenes, seascapes, and night scenes. In fact, he was known to paint from late evening to early morning in order to capture the particular light effects.

Stuber's works were exhibited at the Wilshire Galleries, at Barker Brothers, and at Newhouse Galleries. He was a member of the Painters and Sculptors of Southern California, the Laguna Beach Art Association, the Painters and Sculptors Club, and the Glendale Art Association. Works by Stuber are held at the National Museum of American Art in Washington D.C., the Fleischer Museum in Scottsdale, Arizona, and the Irvine Museum of California.